BDBM50155214 CHEMBL186240::N-(5-Cyclobutyl-thiazol-2-yl)-2-(1H-indol-3-yl)-acetamide

SMILES: O=C(Cc1c[nH]c2ccccc12)Nc1ncc(s1)C1CCC1

InChI Key: InChIKey=HRDHSMRDGZGSBV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50155214   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CDK2/CycE (Homo sapiens (Human))	BDBM50155214 (CHEMBL186240 | N-(5-Cyclobutyl-thiazol-2-yl)-2-(1H...) Show SMILES O=C(Cc1c[nH]c2ccccc12)Nc1ncc(s1)C1CCC1 Show InChI InChI=1S/C17H17N3OS/c21-16(8-12-9-18-14-7-2-1-6-13(12)14)20-17-19-10-15(22-17)11-4-3-5-11/h1-2,6-7,9-11,18H,3-5,8H2,(H,19,20,21)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent-like kinase 5 (Homo sapiens (Human))	BDBM50155214 (CHEMBL186240 | N-(5-Cyclobutyl-thiazol-2-yl)-2-(1H...) Show SMILES O=C(Cc1c[nH]c2ccccc12)Nc1ncc(s1)C1CCC1 Show InChI InChI=1S/C17H17N3OS/c21-16(8-12-9-18-14-7-2-1-6-13(12)14)20-17-19-10-15(22-17)11-4-3-5-11/h1-2,6-7,9-11,18H,3-5,8H2,(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair