BDBM50155499 (R)-3-(4-Methoxy-phenyl)-1-(1-phenyl-2-pyrrolidin-1-yl-ethyl)-1,3,4,7-tetrahydro-azepin-2-one::CHEMBL362329
SMILES: COc1ccc(cc1)[C@H]1CC=CCN(C(CN2CCCC2)c2ccccc2)C1=O
InChI Key: InChIKey=UUZWUUSCTGUCEH-MIHMCVIASA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50155499 ((R)-3-(4-Methoxy-phenyl)-1-(1-phenyl-2-pyrrolidin-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Adolor Corporation Curated by ChEMBL | Assay Description Binding affinity for human Kappa opioid receptor | Bioorg Med Chem Lett 14: 5693-7 (2004) Article DOI: 10.1016/j.bmcl.2004.08.041 BindingDB Entry DOI: 10.7270/Q27D2TMP | |||||||||||
More data for this Ligand-Target Pair |