BDBM50155505 CHEMBL3781414

SMILES: CCN1CCC(CNCc2cc(ccn2)C(O)=O)C1=O

InChI Key: InChIKey=VXOXBJAXVLZQSJ-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50155505   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 6A (KDM6A) (Homo sapiens (Human))	BDBM50155505 (CHEMBL3781414) Show SMILES CCN1CCC(CNCc2cc(ccn2)C(O)=O)C1=O Show InChI InChI=1S/C14H19N3O3/c1-2-17-6-4-11(13(17)18)8-15-9-12-7-10(14(19)20)3-5-16-12/h3,5,7,11,15H,2,4,6,8-9H2,1H3,(H,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of human KDM6A preincubated for 10 mins followed by substrate addition by AlphaLISA assay				ACS Med Chem Lett 7: 128-30 (2016) BindingDB Entry DOI: 10.7270/Q2CJ8GC9
					More data for this Ligand-Target Pair
Histone lysine demethylase PHF8 (Homo sapiens (Human))	BDBM50155505 (CHEMBL3781414) Show SMILES CCN1CCC(CNCc2cc(ccn2)C(O)=O)C1=O Show InChI InChI=1S/C14H19N3O3/c1-2-17-6-4-11(13(17)18)8-15-9-12-7-10(14(19)20)3-5-16-12/h3,5,7,11,15H,2,4,6,8-9H2,1H3,(H,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	<250	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of human PHF8 preincubated for 10 mins followed by substrate addition by AlphaLISA assay				ACS Med Chem Lett 7: 128-30 (2016) BindingDB Entry DOI: 10.7270/Q2CJ8GC9
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM50155505 (CHEMBL3781414) Show SMILES CCN1CCC(CNCc2cc(ccn2)C(O)=O)C1=O Show InChI InChI=1S/C14H19N3O3/c1-2-17-6-4-11(13(17)18)8-15-9-12-7-10(14(19)20)3-5-16-12/h3,5,7,11,15H,2,4,6,8-9H2,1H3,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	<250	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of human KDM5B preincubated for 10 mins followed by substrate addition by AlphaLISA assay				ACS Med Chem Lett 7: 128-30 (2016) BindingDB Entry DOI: 10.7270/Q2CJ8GC9
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM50155505 (CHEMBL3781414) Show SMILES CCN1CCC(CNCc2cc(ccn2)C(O)=O)C1=O Show InChI InChI=1S/C14H19N3O3/c1-2-17-6-4-11(13(17)18)8-15-9-12-7-10(14(19)20)3-5-16-12/h3,5,7,11,15H,2,4,6,8-9H2,1H3,(H,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	<250	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of human KDM4C preincubated for 10 mins followed by substrate addition by AlphaLISA assay				ACS Med Chem Lett 7: 128-30 (2016) BindingDB Entry DOI: 10.7270/Q2CJ8GC9
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM50155505 (CHEMBL3781414) Show SMILES CCN1CCC(CNCc2cc(ccn2)C(O)=O)C1=O Show InChI InChI=1S/C14H19N3O3/c1-2-17-6-4-11(13(17)18)8-15-9-12-7-10(14(19)20)3-5-16-12/h3,5,7,11,15H,2,4,6,8-9H2,1H3,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	<250	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of human KDM2B preincubated for 10 mins followed by substrate addition by AlphaLISA assay				ACS Med Chem Lett 7: 128-30 (2016) BindingDB Entry DOI: 10.7270/Q2CJ8GC9
					More data for this Ligand-Target Pair