BDBM50155579 CHEMBL3546846
SMILES: N[C@@H]1C[C@H]1c1ccc(NC(=O)c2ccccc2)cc1
InChI Key: InChIKey=FFYGOYSNGFPHEN-LSDHHAIUSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
REST corepressor 1 (Homo sapiens (Human)) | BDBM50155579 (CHEMBL3546846) | PDB MMDB Reactome pathway KEGG B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
European Institute of Oncology Curated by ChEMBL | Assay Description Inhibition of human recombinant KDM1A/CoREST expressed in Escherichia coli using mono-methylated H3-K4 peptide as substrate assessed as H2O2 release ... | J Med Chem 59: 1501-17 (2016) BindingDB Entry DOI: 10.7270/Q2086767 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific histone demethylase 1B (Homo sapiens (Human)) | BDBM50155579 (CHEMBL3546846) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.83E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
European Institute of Oncology Curated by ChEMBL | Assay Description Inhibition of KDM1B (unknown origin) | J Med Chem 59: 1501-17 (2016) BindingDB Entry DOI: 10.7270/Q2086767 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM50155579 (CHEMBL3546846) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
European Institute of Oncology Curated by ChEMBL | Assay Description Inhibition of human recombinant MAOB expressed in Pichia pastoris preincubated for 15 mins measured after 30 mins by bioluminescent-coupled assay | J Med Chem 59: 1501-17 (2016) BindingDB Entry DOI: 10.7270/Q2086767 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase (flavin-containing) A (Homo sapiens (Human)) | BDBM50155579 (CHEMBL3546846) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
European Institute of Oncology Curated by ChEMBL | Assay Description Inhibition of human recombinant MAOA expressed in Pichia pastoris preincubated for 15 mins measured after 30 mins by bioluminescent-coupled assay | J Med Chem 59: 1501-17 (2016) BindingDB Entry DOI: 10.7270/Q2086767 | |||||||||||
More data for this Ligand-Target Pair |