BDBM50155670 CHEMBL3780144

SMILES: COc1ccc(cc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1)C#N

InChI Key: InChIKey=MZXGHIXHMAWJJF-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50155670   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50155670 (CHEMBL3780144) Show SMILES COc1ccc(cc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1)C#N Show InChI InChI=1S/C23H21N7O/c1-31-21-8-7-17(14-24)13-20(21)28-9-11-29(12-10-28)22-19-15-27-30(23(19)26-16-25-22)18-5-3-2-4-6-18/h2-8,13,15-16H,9-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...				Bioorg Med Chem Lett 26: 1732-7 (2016) BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Glucose transporter (Homo sapiens (Human))	BDBM50155670 (CHEMBL3780144) Show SMILES COc1ccc(cc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1)C#N Show InChI InChI=1S/C23H21N7O/c1-31-21-8-7-17(14-24)13-20(21)28-9-11-29(12-10-28)22-19-15-27-30(23(19)26-16-25-22)18-5-3-2-4-6-18/h2-8,13,15-16H,9-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in pr...				Bioorg Med Chem Lett 26: 1732-7 (2016) BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155670 (CHEMBL3780144) Show SMILES COc1ccc(cc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1)C#N Show InChI InChI=1S/C23H21N7O/c1-31-21-8-7-17(14-24)13-20(21)28-9-11-29(12-10-28)22-19-15-27-30(23(19)26-16-25-22)18-5-3-2-4-6-18/h2-8,13,15-16H,9-12H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair