null
SMILES: COc1cccc(c1)N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1
InChI Key: InChIKey=STAKKESPUWZRGP-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human)) | BDBM50155681 (CHEMBL3781827) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma AG Curated by ChEMBL | Assay Description Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter... | Bioorg Med Chem Lett 26: 1732-7 (2016) BindingDB Entry DOI: 10.7270/Q2639RM3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human)) | BDBM50155681 (CHEMBL3781827) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.48E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma AG Curated by ChEMBL | Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre... | Bioorg Med Chem Lett 26: 1732-7 (2016) BindingDB Entry DOI: 10.7270/Q2639RM3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human)) | BDBM50155681 (CHEMBL3781827) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma AG Curated by ChEMBL | Assay Description Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in pr... | Bioorg Med Chem Lett 26: 1732-7 (2016) BindingDB Entry DOI: 10.7270/Q2639RM3 | |||||||||||
More data for this Ligand-Target Pair |