BindingDB logo
myBDB logout

null

SMILES: CC(C)CC(=O)c1ccc(OCCCCOc2cccc(F)c2F)c(Br)c1O

InChI Key: InChIKey=HTKSUMYTLRNOEI-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50155699   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))		BDBM50155699
PNG
(1-{3-Bromo-4-[4-(2,3-difluoro-phenoxy)-butoxy]-2-h...)
Show SMILES CC(C)CC(=O)c1ccc(OCCCCOc2cccc(F)c2F)c(Br)c1O
Show InChI InChI=1S/C21H23BrF2O4/c1-13(2)12-16(25)14-8-9-17(19(22)21(14)26)27-10-3-4-11-28-18-7-5-6-15(23)20(18)24/h5-9,13,26H,3-4,10-12H2,1-2H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/an/an/a 558n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human metabotropic glutamate receptor 2 determined by [35S]-GTP gama S binding assay

Bioorg Med Chem Lett 14: 5867-72 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.028
BindingDB Entry DOI: 10.7270/Q2XW4J94
More data for this
Ligand-Target Pair