null

SMILES: CC(C)CC(=O)c1ccc(OCCCCSc2ccccn2)c(C)c1O

InChI Key: InChIKey=XFBJZQIVKIQSON-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50155713   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50155713 (1-{2-Hydroxy-3-methyl-4-[4-(pyridin-2-ylsulfanyl)-...) Show SMILES CC(C)CC(=O)c1ccc(OCCCCSc2ccccn2)c(C)c1O Show InChI InChI=1S/C21H27NO3S/c1-15(2)14-18(23)17-9-10-19(16(3)21(17)24)25-12-6-7-13-26-20-8-4-5-11-22-20/h4-5,8-11,15,24H,6-7,12-14H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	7.3	25
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE US Patent					Assay Description Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...				US Patent US10099993 (2018) BindingDB Entry DOI: 10.7270/Q2Z89FFP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50155713 (1-{2-Hydroxy-3-methyl-4-[4-(pyridin-2-ylsulfanyl)-...) Show SMILES CC(C)CC(=O)c1ccc(OCCCCSc2ccccn2)c(C)c1O Show InChI InChI=1S/C21H27NO3S/c1-15(2)14-18(23)17-9-10-19(16(3)21(17)24)25-12-6-7-13-26-20-8-4-5-11-22-20/h4-5,8-11,15,24H,6-7,12-14H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	US Patent	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE US Patent									US Patent US10099993 (2018) BindingDB Entry DOI: 10.7270/Q2Z89FFP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50155713 (1-{2-Hydroxy-3-methyl-4-[4-(pyridin-2-ylsulfanyl)-...) Show SMILES CC(C)CC(=O)c1ccc(OCCCCSc2ccccn2)c(C)c1O Show InChI InChI=1S/C21H27NO3S/c1-15(2)14-18(23)17-9-10-19(16(3)21(17)24)25-12-6-7-13-26-20-8-4-5-11-22-20/h4-5,8-11,15,24H,6-7,12-14H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	1.53E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human metabotropic glutamate receptor 2 determined by [35S]-GTP gama S binding assay				Bioorg Med Chem Lett 14: 5867-72 (2004) Article DOI: 10.1016/j.bmcl.2004.09.028 BindingDB Entry DOI: 10.7270/Q2XW4J94
					More data for this Ligand-Target Pair