BDBM50155714 CHEMBL3781157

SMILES: COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1

InChI Key: InChIKey=DCMMFESPZVINMW-XADRRFQNSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50155714   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50155714 (CHEMBL3781157) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C26H25Br2ClN4O/c27-19-10-18-7-6-17-11-20(29)12-21(28)23(17)25(24(18)31-15-19)33-9-2-1-5-22(33)26(34)32-14-16-4-3-8-30-13-16/h3-4,8,10-13,15,22,25H,1-2,5-7,9,14H2,(H,32,34)/t22-,25?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...				Bioorg Med Chem Lett 26: 1732-7 (2016) BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155714 (CHEMBL3781157) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C26H25Br2ClN4O/c27-19-10-18-7-6-17-11-20(29)12-21(28)23(17)25(24(18)31-15-19)33-9-2-1-5-22(33)26(34)32-14-16-4-3-8-30-13-16/h3-4,8,10-13,15,22,25H,1-2,5-7,9,14H2,(H,32,34)/t22-,25?/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50155714 (CHEMBL3781157) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C26H25Br2ClN4O/c27-19-10-18-7-6-17-11-20(29)12-21(28)23(17)25(24(18)31-15-19)33-9-2-1-5-22(33)26(34)32-14-16-4-3-8-30-13-16/h3-4,8,10-13,15,22,25H,1-2,5-7,9,14H2,(H,32,34)/t22-,25?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in pr...				Bioorg Med Chem Lett 26: 1732-7 (2016) BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair