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SMILES: COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccn1

InChI Key: InChIKey=GYBUADPJPWFDQT-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50155755   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50155755 (CHEMBL3780349) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccn1 Show InChI InChI=1S/C21H21N7O/c1-29-18-7-3-2-6-17(18)26-10-12-27(13-11-26)20-16-14-25-28(21(16)24-15-23-20)19-8-4-5-9-22-19/h2-9,14-15H,10-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	940	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...				Bioorg Med Chem Lett 26: 1732-7 (2016) BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155755 (CHEMBL3780349) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccn1 Show InChI InChI=1S/C21H21N7O/c1-29-18-7-3-2-6-17(18)26-10-12-27(13-11-26)20-16-14-25-28(21(16)24-15-23-20)19-8-4-5-9-22-19/h2-9,14-15H,10-13H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50155755 (CHEMBL3780349) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccn1 Show InChI InChI=1S/C21H21N7O/c1-29-18-7-3-2-6-17(18)26-10-12-27(13-11-26)20-16-14-25-28(21(16)24-15-23-20)19-8-4-5-9-22-19/h2-9,14-15H,10-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in pr...				Bioorg Med Chem Lett 26: 1732-7 (2016) BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair