BDBM50155759 CHEMBL3781453
SMILES: [H][C@@]12CCC(=C)[C@H](CC[C@H](C)CCO)[C@@]1(C)CCC[C@]2(C)NC(N)=O
InChI Key: InChIKey=ZCRCXSHUPVSSAT-BEUFEYIVSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein-tyrosine phosphatase 1B (Homo sapiens (Human)) | BDBM50155759 (CHEMBL3781453) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 6.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Lucknow Curated by ChEMBL | Assay Description Inhibition of human recombinant PTP-1B using IR5 insulin receptor residues as substrate after 30 mins by malachite green assay | Bioorg Med Chem Lett 26: 1988-92 (2016) BindingDB Entry DOI: 10.7270/Q2514147 | |||||||||||
More data for this Ligand-Target Pair |