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SMILES: CCCN(CCOC)c1cc(C)nc2N(CC(=O)Nc12)c1ccc(cc1Cl)C(C)C

InChI Key: InChIKey=WNTSNTVUEIQHMY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50155965   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Rattus norvegicus (rat))		BDBM50155965
PNG
(4-(2-Chloro-4-isopropyl-phenyl)-8-[(2-methoxy-ethy...)
Show SMILES CCCN(CCOC)c1cc(C)nc2N(CC(=O)Nc12)c1ccc(cc1Cl)C(C)C
Show InChI InChI=1S/C23H31ClN4O2/c1-6-9-27(10-11-30-5)20-12-16(4)25-23-22(20)26-21(29)14-28(23)19-8-7-17(15(2)3)13-18(19)24/h7-8,12-13,15H,6,9-11,14H2,1-5H3,(H,26,29)
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Article
PubMed
n/an/a 2.60n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1

J Med Chem 47: 5783-90 (2004)


Article DOI: 10.1021/jm049737f
BindingDB Entry DOI: 10.7270/Q2S75FT6
More data for this
Ligand-Target Pair