BDBM50156112 CHEMBL3780748

SMILES: COc1ccc2-c3nn(CNC(=O)CN4CCN(CC4)c4ccccc4OC)cc3C(C)(C)Oc2c1

InChI Key: InChIKey=ZKLZJXGGGOMHIM-UHFFFAOYSA-N

Data: 2 KI  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50156112   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50156112 (CHEMBL3780748) Show SMILES COc1ccc2-c3nn(CNC(=O)CN4CCN(CC4)c4ccccc4OC)cc3C(C)(C)Oc2c1 Show InChI InChI=1S/C27H33N5O4/c1-27(2)21-16-32(29-26(21)20-10-9-19(34-3)15-24(20)36-27)18-28-25(33)17-30-11-13-31(14-12-30)22-7-5-6-8-23(22)35-4/h5-10,15-16H,11-14,17-18H2,1-4H3,(H,28,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293 EBNA cells after 90 mins by liquid scintillation spectrophotometer				J Med Chem 59: 1840-53 (2016) BindingDB Entry DOI: 10.7270/Q2BK1F8X
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50156112 (CHEMBL3780748) Show SMILES COc1ccc2-c3nn(CNC(=O)CN4CCN(CC4)c4ccccc4OC)cc3C(C)(C)Oc2c1 Show InChI InChI=1S/C27H33N5O4/c1-27(2)21-16-32(29-26(21)20-10-9-19(34-3)15-24(20)36-27)18-28-25(33)17-30-11-13-31(14-12-30)22-7-5-6-8-23(22)35-4/h5-10,15-16H,11-14,17-18H2,1-4H3,(H,28,33)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 EBNA cells after 90 mins by liquid scintillation spectrophotometer				J Med Chem 59: 1840-53 (2016) BindingDB Entry DOI: 10.7270/Q2BK1F8X
					More data for this Ligand-Target Pair
G-protein coupled receptor 55 (Homo sapiens (Human))	BDBM50156112 (CHEMBL3780748) Show SMILES COc1ccc2-c3nn(CNC(=O)CN4CCN(CC4)c4ccccc4OC)cc3C(C)(C)Oc2c1 Show InChI InChI=1S/C27H33N5O4/c1-27(2)21-16-32(29-26(21)20-10-9-19(34-3)15-24(20)36-27)18-28-25(33)17-30-11-13-31(14-12-30)22-7-5-6-8-23(22)35-4/h5-10,15-16H,11-14,17-18H2,1-4H3,(H,28,33)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	28	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica Curated by ChEMBL					Assay Description Antagonist activity at recombinant human GPR55 expressed in HEK293 cells assessed as inhibition of LPI mediated receptor activation by measuring LPI ...				J Med Chem 59: 1840-53 (2016) BindingDB Entry DOI: 10.7270/Q2BK1F8X
					More data for this Ligand-Target Pair
G-protein coupled receptor 55 (Homo sapiens (Human))	BDBM50156112 (CHEMBL3780748) Show SMILES COc1ccc2-c3nn(CNC(=O)CN4CCN(CC4)c4ccccc4OC)cc3C(C)(C)Oc2c1 Show InChI InChI=1S/C27H33N5O4/c1-27(2)21-16-32(29-26(21)20-10-9-19(34-3)15-24(20)36-27)18-28-25(33)17-30-11-13-31(14-12-30)22-7-5-6-8-23(22)35-4/h5-10,15-16H,11-14,17-18H2,1-4H3,(H,28,33)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	6.40	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica Curated by ChEMBL					Assay Description Partial agonist activity at recombinant human GPR55 expressed in HEK293 cells after 5 mins by xCELLigence assay				J Med Chem 59: 1840-53 (2016) BindingDB Entry DOI: 10.7270/Q2BK1F8X
					More data for this Ligand-Target Pair