BDBM50156174 CHEMBL190811::butyl (5-isobutylthien-2-yl)sulfonylcarbamate derivative
SMILES: CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2cnc3cccnc23)cc1
InChI Key: InChIKey=BCQUNHBYUCGDMW-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Angiotensin II receptor (Homo sapiens (Human)) | BDBM50156174 (CHEMBL190811 | butyl (5-isobutylthien-2-yl)sulfony...) | PDB KEGG DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description Displacement of [125I]-Ang II from pig uterus membrane angiotensin II type 2 (AT2) receptor | J Med Chem 47: 5995-6008 (2004) Article DOI: 10.1021/jm049715t BindingDB Entry DOI: 10.7270/Q29Z95PH | |||||||||||
More data for this Ligand-Target Pair |