BDBM50156179 3-carbamoyl-1-{4-(2-carbamoyl-pyrrolidin-1-yl)-4-oxo-3-[(5-oxo-pyrrolidine-2-carbonyl)-amino]-butyl}-pyridinium;::CHEMBL362358

SMILES: NC(=O)C1CCCN1C(=O)C(CC[n+]1cccc(c1)C(N)=O)NC(=O)C1CCC(=O)N1

InChI Key: InChIKey=QUILMVVCZFJPCG-UHFFFAOYSA-O

Data: 1 KI

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50156179   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thyrotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50156179 (3-carbamoyl-1-{4-(2-carbamoyl-pyrrolidin-1-yl)-4-o...) Show SMILES NC(=O)C1CCCN1C(=O)C(CC[n+]1cccc(c1)C(N)=O)NC(=O)C1CCC(=O)N1 Show InChI InChI=1S/C20H26N6O5/c21-17(28)12-3-1-8-25(11-12)10-7-14(24-19(30)13-5-6-16(27)23-13)20(31)26-9-2-4-15(26)18(22)29/h1,3,8,11,13-15H,2,4-7,9-10H2,(H5-,21,22,23,24,27,28,29,30)/p+1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description Inhibition of [3H]-[3-Me-His2]-TRH binding to thyrotropin releasing hormone receptor of rat forebrain				J Med Chem 47: 6025-33 (2004) Article DOI: 10.1021/jm020531t BindingDB Entry DOI: 10.7270/Q2W095F0
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