BDBM50156255 4-[3-(2-{(R)-(R)-2-Hydroxy-2-[3-(thiophene-2-sulfonylamino)-phenyl]-ethylamino}-propyl)-1H-indol-7-yloxysulfonyl]-benzoic acid::CHEMBL362763

SMILES: C[C@H](Cc1c[nH]c2c(OS(=O)(=O)c3ccc(cc3)C(O)=O)cccc12)NC[C@H](O)c1cccc(NS(=O)(=O)c2cccs2)c1

InChI Key: InChIKey=BSGXQRKXXHVKLG-BCHFMIIMSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50156255   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-2 adrenergic receptor (Homo sapiens (Human))	BDBM50156255 (4-[3-(2-{(R)-(R)-2-Hydroxy-2-[3-(thiophene-2-sulfo...) Show SMILES C[C@H](Cc1c[nH]c2c(OS(=O)(=O)c3ccc(cc3)C(O)=O)cccc12)NC[C@H](O)c1cccc(NS(=O)(=O)c2cccs2)c1 Show InChI InChI=1S/C30H29N3O8S3/c1-19(31-18-26(34)21-5-2-6-23(16-21)33-43(37,38)28-9-4-14-42-28)15-22-17-32-29-25(22)7-3-8-27(29)41-44(39,40)24-12-10-20(11-13-24)30(35)36/h2-14,16-17,19,26,31-34H,15,18H2,1H3,(H,35,36)/t19-,26+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonistic activity was determined by measuring cAMP accumulation in CHO cells expressing cloned human Beta-2 adrenergic receptor				Bioorg Med Chem Lett 14: 5959-62 (2004) Article DOI: 10.1016/j.bmcl.2004.10.035 BindingDB Entry DOI: 10.7270/Q2GQ6X7S
					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Homo sapiens (Human))	BDBM50156255 (4-[3-(2-{(R)-(R)-2-Hydroxy-2-[3-(thiophene-2-sulfo...) Show SMILES C[C@H](Cc1c[nH]c2c(OS(=O)(=O)c3ccc(cc3)C(O)=O)cccc12)NC[C@H](O)c1cccc(NS(=O)(=O)c2cccs2)c1 Show InChI InChI=1S/C30H29N3O8S3/c1-19(31-18-26(34)21-5-2-6-23(16-21)33-43(37,38)28-9-4-14-42-28)15-22-17-32-29-25(22)7-3-8-27(29)41-44(39,40)24-12-10-20(11-13-24)30(35)36/h2-14,16-17,19,26,31-34H,15,18H2,1H3,(H,35,36)/t19-,26+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	85	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Binding inhibition constant was determined by inhibition of [125I]iodocyanopindolol binding to Beta-1 adrenergic receptor				Bioorg Med Chem Lett 14: 5959-62 (2004) Article DOI: 10.1016/j.bmcl.2004.10.035 BindingDB Entry DOI: 10.7270/Q2GQ6X7S
					More data for this Ligand-Target Pair
Beta-3 adrenergic receptor (Homo sapiens (Human))	BDBM50156255 (4-[3-(2-{(R)-(R)-2-Hydroxy-2-[3-(thiophene-2-sulfo...) Show SMILES C[C@H](Cc1c[nH]c2c(OS(=O)(=O)c3ccc(cc3)C(O)=O)cccc12)NC[C@H](O)c1cccc(NS(=O)(=O)c2cccs2)c1 Show InChI InChI=1S/C30H29N3O8S3/c1-19(31-18-26(34)21-5-2-6-23(16-21)33-43(37,38)28-9-4-14-42-28)15-22-17-32-29-25(22)7-3-8-27(29)41-44(39,40)24-12-10-20(11-13-24)30(35)36/h2-14,16-17,19,26,31-34H,15,18H2,1H3,(H,35,36)/t19-,26+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Binding inhibition constant was determined by inhibition of [125I]iodocyanopindolol binding to Beta-3 adrenergic receptor				Bioorg Med Chem Lett 14: 5959-62 (2004) Article DOI: 10.1016/j.bmcl.2004.10.035 BindingDB Entry DOI: 10.7270/Q2GQ6X7S
					More data for this Ligand-Target Pair