BDBM50156350 CHEMBL3785199

SMILES: COCCOc1cnc2ccn([C@H](C)c3nnc4c(F)cc(cn34)-c3cc(C)no3)c(=O)c2c1

InChI Key: InChIKey=IASNQBJQLURUKC-CQSZACIVSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50156350   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50156350 (CHEMBL3785199) Show SMILES COCCOc1cnc2ccn([C@H](C)c3nnc4c(F)cc(cn34)-c3cc(C)no3)c(=O)c2c1 |r| Show InChI InChI=1S/C23H21FN6O4/c1-13-8-20(34-28-13)15-9-18(24)22-27-26-21(30(22)12-15)14(2)29-5-4-19-17(23(29)31)10-16(11-25-19)33-7-6-32-3/h4-5,8-12,14H,6-7H2,1-3H3/t14-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc Curated by ChEMBL					Assay Description Inhibition of recombinant MET (unknown origin) using gastrin peptide as substrate preincubated for 30 mins followed by substrate addition incubated f...				J Med Chem 59: 2328-42 (2016) BindingDB Entry DOI: 10.7270/Q2SN0BVN
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50156350 (CHEMBL3785199) Show SMILES COCCOc1cnc2ccn([C@H](C)c3nnc4c(F)cc(cn34)-c3cc(C)no3)c(=O)c2c1 |r| Show InChI InChI=1S/C23H21FN6O4/c1-13-8-20(34-28-13)15-9-18(24)22-27-26-21(30(22)12-15)14(2)29-5-4-19-17(23(29)31)10-16(11-25-19)33-7-6-32-3/h4-5,8-12,14H,6-7H2,1-3H3/t14-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc Curated by ChEMBL					Assay Description Inhibition of recombinant MET (unknown origin) using gastrin peptide as substrate preincubated for 30 mins followed by substrate addition incubated f...				J Med Chem 59: 2328-42 (2016) BindingDB Entry DOI: 10.7270/Q2SN0BVN
					More data for this Ligand-Target Pair