BDBM50156409 2-Chloro-4-fluoro-N-[3-(1-methyl-piperidin-4-yl)-benzo[d]isoxazol-5-yl]-benzamide::CHEMBL187308

SMILES: CN1CCC(CC1)c1noc2ccc(NC(=O)c3ccc(F)cc3Cl)cc12

InChI Key: InChIKey=KVIHIAIJXYTYLJ-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50156409   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin (5-HT) receptor (Homo sapiens (Human))	BDBM50156409 (2-Chloro-4-fluoro-N-[3-(1-methyl-piperidin-4-yl)-b...) Show SMILES CN1CCC(CC1)c1noc2ccc(NC(=O)c3ccc(F)cc3Cl)cc12 Show InChI InChI=1S/C20H19ClFN3O2/c1-25-8-6-12(7-9-25)19-16-11-14(3-5-18(16)27-24-19)23-20(26)15-4-2-13(22)10-17(15)21/h2-5,10-12H,6-9H2,1H3,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1F receptor				Bioorg Med Chem Lett 14: 6011-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.079 BindingDB Entry DOI: 10.7270/Q23J3CFK
					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Homo sapiens (Human))	BDBM50156409 (2-Chloro-4-fluoro-N-[3-(1-methyl-piperidin-4-yl)-b...) Show SMILES CN1CCC(CC1)c1noc2ccc(NC(=O)c3ccc(F)cc3Cl)cc12 Show InChI InChI=1S/C20H19ClFN3O2/c1-25-8-6-12(7-9-25)19-16-11-14(3-5-18(16)27-24-19)23-20(26)15-4-2-13(22)10-17(15)21/h2-5,10-12H,6-9H2,1H3,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Stimulation of [35S]-GTP-gammaS, binding to cloned human 5-hydroxytryptamine 1F receptor expressed in Mouse LM(tk-) cells				Bioorg Med Chem Lett 14: 6011-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.079 BindingDB Entry DOI: 10.7270/Q23J3CFK
					More data for this Ligand-Target Pair