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BDBM50156421 (R)-1-{4-[5-(2,4-Dichloro-phenyl)-[1,2,4]oxadiazol-3-ylmethyl]-piperazin-1-yl}-3-(2-methyl-benzothiazol-5-yloxy)-propan-2-ol::CHEMBL186976

SMILES: Cc1nc2cc(OC[C@H](O)CN3CCN(Cc4noc(n4)-c4ccc(Cl)cc4Cl)CC3)ccc2s1

InChI Key: InChIKey=FNBDBCKSGVMDQY-QGZVFWFLSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50156421   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Palmitoyl-CoA oxidase


(Rattus norvegicus)
BDBM50156421
PNG
((R)-1-{4-[5-(2,4-Dichloro-phenyl)-[1,2,4]oxadiazol...)
Show SMILES Cc1nc2cc(OC[C@H](O)CN3CCN(Cc4noc(n4)-c4ccc(Cl)cc4Cl)CC3)ccc2s1
Show InChI InChI=1S/C24H25Cl2N5O3S/c1-15-27-21-11-18(3-5-22(21)35-15)33-14-17(32)12-30-6-8-31(9-7-30)13-23-28-24(34-29-23)19-4-2-16(25)10-20(19)26/h2-5,10-11,17,32H,6-9,12-14H2,1H3/t17-/m1/s1
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PC cid
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n/an/a 130n/an/an/an/an/an/a



CV Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibition of palmitoyl-CoA oxidation in rat heart mitochondria


Bioorg Med Chem Lett 14: 6017-21 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.077
More data for this
Ligand-Target Pair