BDBM50156430 (R)-1-{(S)-4-[5-(2,4-Dichloro-phenyl)-[1,2,4]oxadiazol-3-ylmethyl]-2-methyl-piperazin-1-yl}-3-(2-methyl-benzothiazol-5-yloxy)-propan-2-ol::CHEMBL185174
SMILES: C[C@H]1CN(Cc2noc(n2)-c2ccc(Cl)cc2Cl)CCN1C[C@@H](O)COc1ccc2sc(C)nc2c1
InChI Key: InChIKey=PLGJMSIIMZDAQM-MAUKXSAKSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Palmitoyl-CoA oxidase (Rattus norvegicus) | BDBM50156430 ((R)-1-{(S)-4-[5-(2,4-Dichloro-phenyl)-[1,2,4]oxadi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
CV Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of palmitoyl-CoA oxidation in rat heart mitochondria | Bioorg Med Chem Lett 14: 6017-21 (2004) Article DOI: 10.1016/j.bmcl.2004.09.077 BindingDB Entry DOI: 10.7270/Q2ZS2W0R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Palmitoyl-CoA oxidase (Rattus norvegicus) | BDBM50156430 ((R)-1-{(S)-4-[5-(2,4-Dichloro-phenyl)-[1,2,4]oxadi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
CV Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of palmitoyl-CoA oxidation in rat heart mitochondria | Bioorg Med Chem Lett 14: 6017-21 (2004) Article DOI: 10.1016/j.bmcl.2004.09.077 BindingDB Entry DOI: 10.7270/Q2ZS2W0R | |||||||||||
More data for this Ligand-Target Pair |