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BDBM50156434 4-(3-{4-[(R)-2-Hydroxy-3-(2-methyl-benzothiazol-5-yloxy)-propyl]-piperazin-1-ylmethyl}-[1,2,4]oxadiazol-5-yl)-benzonitrile::CHEMBL187231

SMILES: Cc1nc2cc(OC[C@H](O)CN3CCN(Cc4noc(n4)-c4ccc(cc4)C#N)CC3)ccc2s1

InChI Key: InChIKey=AWVFXNHALITFRV-HXUWFJFHSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50156434   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Palmitoyl-CoA oxidase


(Rattus norvegicus)
BDBM50156434
PNG
(4-(3-{4-[(R)-2-Hydroxy-3-(2-methyl-benzothiazol-5-...)
Show SMILES Cc1nc2cc(OC[C@H](O)CN3CCN(Cc4noc(n4)-c4ccc(cc4)C#N)CC3)ccc2s1
Show InChI InChI=1S/C25H26N6O3S/c1-17-27-22-12-21(6-7-23(22)35-17)33-16-20(32)14-30-8-10-31(11-9-30)15-24-28-25(34-29-24)19-4-2-18(13-26)3-5-19/h2-7,12,20,32H,8-11,14-16H2,1H3/t20-/m1/s1
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PC cid
PC sid
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Article
PubMed
n/an/a 4.41E+3n/an/an/an/an/an/a



CV Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibition of palmitoyl-CoA oxidation in rat heart mitochondria


Bioorg Med Chem Lett 14: 6017-21 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.077
More data for this
Ligand-Target Pair