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BDBM50156435 (R)-1-(2-Methyl-benzothiazol-5-yloxy)-3-{4-[3-(4-trifluoromethyl-phenyl)-[1,2,4]oxadiazol-5-ylmethyl]-piperazin-1-yl}-propan-2-ol::CHEMBL186256

SMILES: Cc1nc2cc(OC[C@H](O)CN3CCN(Cc4nc(no4)-c4ccc(cc4)C(F)(F)F)CC3)ccc2s1

InChI Key: InChIKey=OZSCWIMSAIWZJM-LJQANCHMSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50156435   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Palmitoyl-CoA oxidase


(Rattus norvegicus)
BDBM50156435
PNG
((R)-1-(2-Methyl-benzothiazol-5-yloxy)-3-{4-[3-(4-t...)
Show SMILES Cc1nc2cc(OC[C@H](O)CN3CCN(Cc4nc(no4)-c4ccc(cc4)C(F)(F)F)CC3)ccc2s1
Show InChI InChI=1S/C25H26F3N5O3S/c1-16-29-21-12-20(6-7-22(21)37-16)35-15-19(34)13-32-8-10-33(11-9-32)14-23-30-24(31-36-23)17-2-4-18(5-3-17)25(26,27)28/h2-7,12,19,34H,8-11,13-15H2,1H3/t19-/m1/s1
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PC cid
PC sid
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Article
PubMed
n/an/a 3.63E+3n/an/an/an/an/an/a



CV Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibition of palmitoyl-CoA oxidation in rat heart mitochondria


Bioorg Med Chem Lett 14: 6017-21 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.077
More data for this
Ligand-Target Pair