BDBM50156436 (R)-1-(2-Methyl-benzothiazol-5-yloxy)-3-{4-[2-(4-trifluoromethyl-phenyl)-thiazol-4-ylmethyl]-piperazin-1-yl}-propan-2-ol::CHEMBL184758

SMILES: Cc1nc2cc(OC[C@H](O)CN3CCN(Cc4csc(n4)-c4ccc(cc4)C(F)(F)F)CC3)ccc2s1

InChI Key: InChIKey=WJCQAKVHUXMDLE-OAQYLSRUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50156436   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Palmitoyl-CoA oxidase (Rattus norvegicus)	BDBM50156436 ((R)-1-(2-Methyl-benzothiazol-5-yloxy)-3-{4-[2-(4-t...) Show SMILES Cc1nc2cc(OC[C@H](O)CN3CCN(Cc4csc(n4)-c4ccc(cc4)C(F)(F)F)CC3)ccc2s1 Show InChI InChI=1S/C26H27F3N4O2S2/c1-17-30-23-12-22(6-7-24(23)37-17)35-15-21(34)14-33-10-8-32(9-11-33)13-20-16-36-25(31-20)18-2-4-19(5-3-18)26(27,28)29/h2-7,12,16,21,34H,8-11,13-15H2,1H3/t21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
CV Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of palmitoyl-CoA oxidation in rat heart mitochondria				Bioorg Med Chem Lett 14: 6017-21 (2004) Article DOI: 10.1016/j.bmcl.2004.09.077 BindingDB Entry DOI: 10.7270/Q2ZS2W0R
					More data for this Ligand-Target Pair