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BDBM50156436 (R)-1-(2-Methyl-benzothiazol-5-yloxy)-3-{4-[2-(4-trifluoromethyl-phenyl)-thiazol-4-ylmethyl]-piperazin-1-yl}-propan-2-ol::CHEMBL184758

SMILES: Cc1nc2cc(OC[C@H](O)CN3CCN(Cc4csc(n4)-c4ccc(cc4)C(F)(F)F)CC3)ccc2s1

InChI Key: InChIKey=WJCQAKVHUXMDLE-OAQYLSRUSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50156436   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Palmitoyl-CoA oxidase


(Rattus norvegicus)
BDBM50156436
PNG
((R)-1-(2-Methyl-benzothiazol-5-yloxy)-3-{4-[2-(4-t...)
Show SMILES Cc1nc2cc(OC[C@H](O)CN3CCN(Cc4csc(n4)-c4ccc(cc4)C(F)(F)F)CC3)ccc2s1
Show InChI InChI=1S/C26H27F3N4O2S2/c1-17-30-23-12-22(6-7-24(23)37-17)35-15-21(34)14-33-10-8-32(9-11-33)13-20-16-36-25(31-20)18-2-4-19(5-3-18)26(27,28)29/h2-7,12,16,21,34H,8-11,13-15H2,1H3/t21-/m1/s1
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MMDB

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PC cid
PC sid
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Article
PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



CV Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibition of palmitoyl-CoA oxidation in rat heart mitochondria


Bioorg Med Chem Lett 14: 6017-21 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.077
More data for this
Ligand-Target Pair