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BDBM50156437 (R)-1-{4-[5-(3-Chloro-phenyl)-[1,2,4]oxadiazol-3-ylmethyl]-piperazin-1-yl}-3-(2-methyl-benzothiazol-5-yloxy)-propan-2-ol::CHEMBL186257

SMILES: Cc1nc2cc(OC[C@H](O)CN3CCN(Cc4noc(n4)-c4cccc(Cl)c4)CC3)ccc2s1

InChI Key: InChIKey=YCXMIYHFLJBIGG-LJQANCHMSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50156437   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Palmitoyl-CoA oxidase


(Rattus norvegicus)
BDBM50156437
PNG
((R)-1-{4-[5-(3-Chloro-phenyl)-[1,2,4]oxadiazol-3-y...)
Show SMILES Cc1nc2cc(OC[C@H](O)CN3CCN(Cc4noc(n4)-c4cccc(Cl)c4)CC3)ccc2s1
Show InChI InChI=1S/C24H26ClN5O3S/c1-16-26-21-12-20(5-6-22(21)34-16)32-15-19(31)13-29-7-9-30(10-8-29)14-23-27-24(33-28-23)17-3-2-4-18(25)11-17/h2-6,11-12,19,31H,7-10,13-15H2,1H3/t19-/m1/s1
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PC cid
PC sid
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Article
PubMed
n/an/a 4.12E+3n/an/an/an/an/an/a



CV Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibition of palmitoyl-CoA oxidation in rat heart mitochondria


Bioorg Med Chem Lett 14: 6017-21 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.077
More data for this
Ligand-Target Pair