BDBM50156439 (R)-1-(2-Methyl-benzothiazol-5-yloxy)-3-{4-[5-(4-trifluoromethyl-phenyl)-[1,3,4]oxadiazol-2-ylmethyl]-piperazin-1-yl}-propan-2-ol::CHEMBL186837

SMILES: Cc1nc2cc(OC[C@H](O)CN3CCN(Cc4nnc(o4)-c4ccc(cc4)C(F)(F)F)CC3)ccc2s1

InChI Key: InChIKey=YVINUCTXLVXVHS-LJQANCHMSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50156439   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Palmitoyl-CoA oxidase (Rattus norvegicus)	BDBM50156439 ((R)-1-(2-Methyl-benzothiazol-5-yloxy)-3-{4-[5-(4-t...) Show SMILES Cc1nc2cc(OC[C@H](O)CN3CCN(Cc4nnc(o4)-c4ccc(cc4)C(F)(F)F)CC3)ccc2s1 Show InChI InChI=1S/C25H26F3N5O3S/c1-16-29-21-12-20(6-7-22(21)37-16)35-15-19(34)13-32-8-10-33(11-9-32)14-23-30-31-24(36-23)17-2-4-18(5-3-17)25(26,27)28/h2-7,12,19,34H,8-11,13-15H2,1H3/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
CV Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of palmitoyl-CoA oxidation in rat heart mitochondria				Bioorg Med Chem Lett 14: 6017-21 (2004) Article DOI: 10.1016/j.bmcl.2004.09.077 BindingDB Entry DOI: 10.7270/Q2ZS2W0R
					More data for this Ligand-Target Pair