BDBM50156479 5-((S)-2-Oxo-4-phenyl-imidazolidine-1-sulfonyl)-2,3-dihydro-indole-1-carboxylic acid (2-morpholin-4-yl-ethyl)-amide::CHEMBL363690

SMILES: O=C(NCCN1CCOCC1)N1CCc2cc(ccc12)S(=O)(=O)N1C[C@@H](NC1=O)c1ccccc1

InChI Key: InChIKey=GSEUYCFBUGHNEF-OAQYLSRUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50156479   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tubulin beta chain [1-43] (Leishmania donovani)	BDBM50156479 (5-((S)-2-Oxo-4-phenyl-imidazolidine-1-sulfonyl)-2,...) Show SMILES O=C(NCCN1CCOCC1)N1CCc2cc(ccc12)S(=O)(=O)N1C[C@@H](NC1=O)c1ccccc1 Show InChI InChI=1S/C24H29N5O5S/c30-23(25-9-11-27-12-14-34-15-13-27)28-10-8-19-16-20(6-7-22(19)28)35(32,33)29-17-21(26-24(29)31)18-4-2-1-3-5-18/h1-7,16,21H,8-15,17H2,(H,25,30)(H,26,31)/t21-/m1/s1	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
LG Life Sciences, Ltd Curated by ChEMBL					Assay Description Compound was tested for inhibition of tubulin polymerisation				Bioorg Med Chem Lett 14: 6075-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.069 BindingDB Entry DOI: 10.7270/Q269731X
					More data for this Ligand-Target Pair