BDBM50156482 4-Amino-N-[2-chloro-4-((S)-2-oxo-4-phenyl-imidazolidine-1-sulfonyl)-phenyl]-benzamide::CHEMBL362529

SMILES: Nc1ccc(cc1)C(=O)Nc1ccc(cc1Cl)S(=O)(=O)N1C[C@@H](NC1=O)c1ccccc1

InChI Key: InChIKey=OJGGGWVKDALWMY-HXUWFJFHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50156482   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tubulin beta chain [1-43] (Leishmania donovani)	BDBM50156482 (4-Amino-N-[2-chloro-4-((S)-2-oxo-4-phenyl-imidazol...) Show SMILES Nc1ccc(cc1)C(=O)Nc1ccc(cc1Cl)S(=O)(=O)N1C[C@@H](NC1=O)c1ccccc1 Show InChI InChI=1S/C22H19ClN4O4S/c23-18-12-17(10-11-19(18)25-21(28)15-6-8-16(24)9-7-15)32(30,31)27-13-20(26-22(27)29)14-4-2-1-3-5-14/h1-12,20H,13,24H2,(H,25,28)(H,26,29)/t20-/m1/s1	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
LG Life Sciences, Ltd Curated by ChEMBL					Assay Description Compound was tested for inhibition of tubulin polymerisation				Bioorg Med Chem Lett 14: 6075-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.069 BindingDB Entry DOI: 10.7270/Q269731X
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