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SMILES: Nc1ccc(cc1)C(=O)N1CCc2cc(ccc12)S(=O)(=O)N1CC(NC1=O)c1cccs1

InChI Key: InChIKey=YXNNLTNWJBFEOJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50156485   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tubulin beta chain [1-43]


(Leishmania donovani)		BDBM50156485
PNG
(1-[1-(4-Amino-benzoyl)-2,3-dihydro-1H-indole-5-sul...)
Show SMILES Nc1ccc(cc1)C(=O)N1CCc2cc(ccc12)S(=O)(=O)N1CC(NC1=O)c1cccs1
Show InChI InChI=1S/C22H20N4O4S2/c23-16-5-3-14(4-6-16)21(27)25-10-9-15-12-17(7-8-19(15)25)32(29,30)26-13-18(24-22(26)28)20-2-1-11-31-20/h1-8,11-12,18H,9-10,13,23H2,(H,24,28)
UniProtKB/SwissProt

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PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.05E+4n/an/an/an/an/an/a



LG Life Sciences, Ltd

Curated by ChEMBL


Assay Description
Compound was tested for inhibition of tubulin polymerisation

Bioorg Med Chem Lett 14: 6075-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.069
BindingDB Entry DOI: 10.7270/Q269731X
More data for this
Ligand-Target Pair