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SMILES: O=C(N1CCc2cc(ccc12)S(=O)(=O)N1CC(NC1=O)c1cccs1)c1ccco1

InChI Key: InChIKey=QHXAXKSLTKRPSH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50156488   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tubulin beta chain [1-43]


(Leishmania donovani)		BDBM50156488
PNG
(1-[1-(Furan-2-carbonyl)-2,3-dihydro-1H-indole-5-su...)
Show SMILES O=C(N1CCc2cc(ccc12)S(=O)(=O)N1CC(NC1=O)c1cccs1)c1ccco1
Show InChI InChI=1S/C20H17N3O5S2/c24-19(17-3-1-9-28-17)22-8-7-13-11-14(5-6-16(13)22)30(26,27)23-12-15(21-20(23)25)18-4-2-10-29-18/h1-6,9-11,15H,7-8,12H2,(H,21,25)
UniProtKB/SwissProt

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PC sid
UniChem

Similars
Article
PubMed
n/an/a 4.00E+3n/an/an/an/an/an/a



LG Life Sciences, Ltd

Curated by ChEMBL


Assay Description
Compound was tested for inhibition of tubulin polymerisation

Bioorg Med Chem Lett 14: 6075-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.069
BindingDB Entry DOI: 10.7270/Q269731X
More data for this
Ligand-Target Pair