BDBM50156493 1-[1-(4-Amino-benzoyl)-2,3-dihydro-1H-indole-5-sulfonyl]-4-(4-fluoro-phenyl)-imidazolidin-2-one::CHEMBL187716

SMILES: Nc1ccc(cc1)C(=O)N1CCc2cc(ccc12)S(=O)(=O)N1CC(NC1=O)c1ccc(F)cc1

InChI Key: InChIKey=AISRCZMZSLSDTC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50156493   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tubulin beta chain [1-43] (Leishmania donovani)	BDBM50156493 (1-[1-(4-Amino-benzoyl)-2,3-dihydro-1H-indole-5-sul...) Show SMILES Nc1ccc(cc1)C(=O)N1CCc2cc(ccc12)S(=O)(=O)N1CC(NC1=O)c1ccc(F)cc1 Show InChI InChI=1S/C24H21FN4O4S/c25-18-5-1-15(2-6-18)21-14-29(24(31)27-21)34(32,33)20-9-10-22-17(13-20)11-12-28(22)23(30)16-3-7-19(26)8-4-16/h1-10,13,21H,11-12,14,26H2,(H,27,31)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
LG Life Sciences, Ltd Curated by ChEMBL					Assay Description Compound was tested for inhibition of tubulin polymerisation				Bioorg Med Chem Lett 14: 6075-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.069 BindingDB Entry DOI: 10.7270/Q269731X
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