BDBM50156527 2-(4-tert-Butyl-phenoxy)-2-methyl-3-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-phenyl}-propionic acid::CHEMBL187258

SMILES: Cc1oc(nc1CCOc1ccc(CC(C)(Oc2ccc(cc2)C(C)(C)C)C(O)=O)cc1)-c1ccccc1

InChI Key: InChIKey=KKXGQUOGYDUWOF-UHFFFAOYSA-N

Data: 2 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50156527   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50156527 (2-(4-tert-Butyl-phenoxy)-2-methyl-3-{4-[2-(5-methy...) Show SMILES Cc1oc(nc1CCOc1ccc(CC(C)(Oc2ccc(cc2)C(C)(C)C)C(O)=O)cc1)-c1ccccc1 Show InChI InChI=1S/C32H35NO5/c1-22-28(33-29(37-22)24-9-7-6-8-10-24)19-20-36-26-15-11-23(12-16-26)21-32(5,30(34)35)38-27-17-13-25(14-18-27)31(2,3)4/h6-18H,19-21H2,1-5H3,(H,34,35)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	149	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of human Peroxisome proliferator activated receptor alpha				Bioorg Med Chem Lett 14: 6113-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.031 BindingDB Entry DOI: 10.7270/Q2QN67J1
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50156527 (2-(4-tert-Butyl-phenoxy)-2-methyl-3-{4-[2-(5-methy...) Show SMILES Cc1oc(nc1CCOc1ccc(CC(C)(Oc2ccc(cc2)C(C)(C)C)C(O)=O)cc1)-c1ccccc1 Show InChI InChI=1S/C32H35NO5/c1-22-28(33-29(37-22)24-9-7-6-8-10-24)19-20-36-26-15-11-23(12-16-26)21-32(5,30(34)35)38-27-17-13-25(14-18-27)31(2,3)4/h6-18H,19-21H2,1-5H3,(H,34,35)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Transactivation activity for human Peroxisome proliferator activated receptor alpha				Bioorg Med Chem Lett 14: 6113-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.031 BindingDB Entry DOI: 10.7270/Q2QN67J1
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Mus musculus)	BDBM50156527 (2-(4-tert-Butyl-phenoxy)-2-methyl-3-{4-[2-(5-methy...) Show SMILES Cc1oc(nc1CCOc1ccc(CC(C)(Oc2ccc(cc2)C(C)(C)C)C(O)=O)cc1)-c1ccccc1 Show InChI InChI=1S/C32H35NO5/c1-22-28(33-29(37-22)24-9-7-6-8-10-24)19-20-36-26-15-11-23(12-16-26)21-32(5,30(34)35)38-27-17-13-25(14-18-27)31(2,3)4/h6-18H,19-21H2,1-5H3,(H,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	211	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Transactivation activity for mouse Peroxisome proliferator activated receptor alpha				Bioorg Med Chem Lett 14: 6113-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.031 BindingDB Entry DOI: 10.7270/Q2QN67J1
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Mus musculus)	BDBM50156527 (2-(4-tert-Butyl-phenoxy)-2-methyl-3-{4-[2-(5-methy...) Show SMILES Cc1oc(nc1CCOc1ccc(CC(C)(Oc2ccc(cc2)C(C)(C)C)C(O)=O)cc1)-c1ccccc1 Show InChI InChI=1S/C32H35NO5/c1-22-28(33-29(37-22)24-9-7-6-8-10-24)19-20-36-26-15-11-23(12-16-26)21-32(5,30(34)35)38-27-17-13-25(14-18-27)31(2,3)4/h6-18H,19-21H2,1-5H3,(H,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	515	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of mouse Peroxisome proliferator activated receptor alpha				Bioorg Med Chem Lett 14: 6113-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.031 BindingDB Entry DOI: 10.7270/Q2QN67J1
					More data for this Ligand-Target Pair