BDBM50156747 (S)-3-(4-(isobutylamino)-6-(pyrrolidin-3-ylamino)-1,3,5-triazin-2-ylamino)-4-methylbenzamide::CHEMBL413783

SMILES: CC(C)CNc1nc(N[C@H]2CCNC2)nc(Nc2cc(ccc2C)C(N)=O)n1

InChI Key: InChIKey=NHUQUICYOIWRBS-AWEZNQCLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50156747   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50156747 ((S)-3-(4-(isobutylamino)-6-(pyrrolidin-3-ylamino)-...) Show SMILES CC(C)CNc1nc(N[C@H]2CCNC2)nc(Nc2cc(ccc2C)C(N)=O)n1 |r| Show InChI InChI=1S/C19H28N8O/c1-11(2)9-22-17-25-18(23-14-6-7-21-10-14)27-19(26-17)24-15-8-13(16(20)28)5-4-12(15)3/h4-5,8,11,14,21H,6-7,9-10H2,1-3H3,(H2,20,28)(H3,22,23,24,25,26,27)/t14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human p38-alpha expressed in Escherichia coli				J Med Chem 47: 6283-91 (2004) Article DOI: 10.1021/jm049521d BindingDB Entry DOI: 10.7270/Q2WS8SR1
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