BDBM50156814 CHEMBL3792731

SMILES: Clc1ccc(CN2CCO[C@H](CSc3ccccc3)C2)cc1

InChI Key: InChIKey=XINSSTGUTQPDTR-KRWDZBQOSA-N

Data: 6 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50156814   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50156814 (CHEMBL3792731) Show SMILES Clc1ccc(CN2CCO[C@H](CSc3ccccc3)C2)cc1 |r| Show InChI InChI=1S/C18H20ClNOS/c19-16-8-6-15(7-9-16)12-20-10-11-21-17(13-20)14-22-18-4-2-1-3-5-18/h1-9,17H,10-14H2/t17-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cells				Bioorg Med Chem Lett 26: 2481-8 (2016) BindingDB Entry DOI: 10.7270/Q2G44S5M
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50156814 (CHEMBL3792731) Show SMILES Clc1ccc(CN2CCO[C@H](CSc3ccccc3)C2)cc1 |r| Show InChI InChI=1S/C18H20ClNOS/c19-16-8-6-15(7-9-16)12-20-10-11-21-17(13-20)14-22-18-4-2-1-3-5-18/h1-9,17H,10-14H2/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of [3H]-Spiperone from human recombinant dopamine D2L receptor expressed in CHO cells				Bioorg Med Chem Lett 26: 2481-8 (2016) BindingDB Entry DOI: 10.7270/Q2G44S5M
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50156814 (CHEMBL3792731) Show SMILES Clc1ccc(CN2CCO[C@H](CSc3ccccc3)C2)cc1 |r| Show InChI InChI=1S/C18H20ClNOS/c19-16-8-6-15(7-9-16)12-20-10-11-21-17(13-20)14-22-18-4-2-1-3-5-18/h1-9,17H,10-14H2/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of [3H]-Spiperone from human recombinant dopamine D2S receptor expressed in CHO cells				Bioorg Med Chem Lett 26: 2481-8 (2016) BindingDB Entry DOI: 10.7270/Q2G44S5M
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50156814 (CHEMBL3792731) Show SMILES Clc1ccc(CN2CCO[C@H](CSc3ccccc3)C2)cc1 |r| Show InChI InChI=1S/C18H20ClNOS/c19-16-8-6-15(7-9-16)12-20-10-11-21-17(13-20)14-22-18-4-2-1-3-5-18/h1-9,17H,10-14H2/t17-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of [3H]-SCH-23390 from human recombinant dopamine D5 receptor expressed in CHO cells				Bioorg Med Chem Lett 26: 2481-8 (2016) BindingDB Entry DOI: 10.7270/Q2G44S5M
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50156814 (CHEMBL3792731) Show SMILES Clc1ccc(CN2CCO[C@H](CSc3ccccc3)C2)cc1 |r| Show InChI InChI=1S/C18H20ClNOS/c19-16-8-6-15(7-9-16)12-20-10-11-21-17(13-20)14-22-18-4-2-1-3-5-18/h1-9,17H,10-14H2/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of [3H]-SCH-23390 from human recombinant dopamine D1 receptor expressed in CHO cells				Bioorg Med Chem Lett 26: 2481-8 (2016) BindingDB Entry DOI: 10.7270/Q2G44S5M
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50156814 (CHEMBL3792731) Show SMILES Clc1ccc(CN2CCO[C@H](CSc3ccccc3)C2)cc1 |r| Show InChI InChI=1S/C18H20ClNOS/c19-16-8-6-15(7-9-16)12-20-10-11-21-17(13-20)14-22-18-4-2-1-3-5-18/h1-9,17H,10-14H2/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of [3H]-Spiperone from human recombinant dopamine D3 receptor expressed in CHO cells				Bioorg Med Chem Lett 26: 2481-8 (2016) BindingDB Entry DOI: 10.7270/Q2G44S5M
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50156814 (CHEMBL3792731) Show SMILES Clc1ccc(CN2CCO[C@H](CSc3ccccc3)C2)cc1 |r| Show InChI InChI=1S/C18H20ClNOS/c19-16-8-6-15(7-9-16)12-20-10-11-21-17(13-20)14-22-18-4-2-1-3-5-18/h1-9,17H,10-14H2/t17-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cells				Bioorg Med Chem Lett 26: 2481-8 (2016) BindingDB Entry DOI: 10.7270/Q2G44S5M
					More data for this Ligand-Target Pair