null

SMILES: CCOCCn1cc(C2CCN(Cc3ccc(OCC(O)=O)cc3)CC2)c2ccccc12

InChI Key: InChIKey=SKBJEXJAGCSGRL-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50156851   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50156851 (2-(4-((4-(1-(2-ethoxyethyl)-1H-indol-3-yl)piperidi...) Show SMILES CCOCCn1cc(C2CCN(Cc3ccc(OCC(O)=O)cc3)CC2)c2ccccc12 Show InChI InChI=1S/C26H32N2O4/c1-2-31-16-15-28-18-24(23-5-3-4-6-25(23)28)21-11-13-27(14-12-21)17-20-7-9-22(10-8-20)32-19-26(29)30/h3-10,18,21H,2,11-17,19H2,1H3,(H,29,30)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	322	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Displacement of [3H]mepyramine from histamine H1 receptor in guinea pig cerebellum membranes				J Med Chem 47: 6326-37 (2004) Article DOI: 10.1021/jm0498203 BindingDB Entry DOI: 10.7270/Q2HM57XC
					More data for this Ligand-Target Pair
Histamine H2 receptor (Homo sapiens (Human))	BDBM50156851 (2-(4-((4-(1-(2-ethoxyethyl)-1H-indol-3-yl)piperidi...) Show SMILES CCOCCn1cc(C2CCN(Cc3ccc(OCC(O)=O)cc3)CC2)c2ccccc12 Show InChI InChI=1S/C26H32N2O4/c1-2-31-16-15-28-18-24(23-5-3-4-6-25(23)28)21-11-13-27(14-12-21)17-20-7-9-22(10-8-20)32-19-26(29)30/h3-10,18,21H,2,11-17,19H2,1H3,(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Displacement of [3H]ketanserine from histamine H2 receptor in human cortex membranes				J Med Chem 47: 6326-37 (2004) Article DOI: 10.1021/jm0498203 BindingDB Entry DOI: 10.7270/Q2HM57XC
					More data for this Ligand-Target Pair