null

SMILES: CCOCCn1cc(C2CCN(CCOc3ccccc3C(O)=O)CC2)c2ccc(F)cc12

InChI Key: InChIKey=BVRIYQUZSCWOSG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50156857   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50156857 (2-(2-(4-(1-(2-ethoxyethyl)-6-fluoro-1H-indol-3-yl)...) Show SMILES CCOCCn1cc(C2CCN(CCOc3ccccc3C(O)=O)CC2)c2ccc(F)cc12 Show InChI InChI=1S/C26H31FN2O4/c1-2-32-15-14-29-18-23(21-8-7-20(27)17-24(21)29)19-9-11-28(12-10-19)13-16-33-25-6-4-3-5-22(25)26(30)31/h3-8,17-19H,2,9-16H2,1H3,(H,30,31)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Displacement of [3H]mepyramine from histamine H1 receptor in guinea pig cerebellum membranes				J Med Chem 47: 6326-37 (2004) Article DOI: 10.1021/jm0498203 BindingDB Entry DOI: 10.7270/Q2HM57XC
					More data for this Ligand-Target Pair
Histamine H2 receptor (Homo sapiens (Human))	BDBM50156857 (2-(2-(4-(1-(2-ethoxyethyl)-6-fluoro-1H-indol-3-yl)...) Show SMILES CCOCCn1cc(C2CCN(CCOc3ccccc3C(O)=O)CC2)c2ccc(F)cc12 Show InChI InChI=1S/C26H31FN2O4/c1-2-32-15-14-29-18-23(21-8-7-20(27)17-24(21)29)19-9-11-28(12-10-19)13-16-33-25-6-4-3-5-22(25)26(30)31/h3-8,17-19H,2,9-16H2,1H3,(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Displacement of [3H]ketanserine from histamine H2 receptor in human cortex membranes				J Med Chem 47: 6326-37 (2004) Article DOI: 10.1021/jm0498203 BindingDB Entry DOI: 10.7270/Q2HM57XC
					More data for this Ligand-Target Pair