null

SMILES: COCCn1cc(C2CCN(Cc3cccc(c3)C(O)=O)CC2)c2ccc(F)cc12

InChI Key: InChIKey=ZPJLZUVFWGUUTM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50156858   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50156858 (3-{4-[6-fluoro-1-(2-methoxyethyl)-1H-indol-3-yl]pi...) Show SMILES COCCn1cc(C2CCN(Cc3cccc(c3)C(O)=O)CC2)c2ccc(F)cc12 Show InChI InChI=1S/C24H27FN2O3/c1-30-12-11-27-16-22(21-6-5-20(25)14-23(21)27)18-7-9-26(10-8-18)15-17-3-2-4-19(13-17)24(28)29/h2-6,13-14,16,18H,7-12,15H2,1H3,(H,28,29)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Displacement of [3H]mepyramine from histamine H1 receptor in guinea pig cerebellum membranes				J Med Chem 47: 6326-37 (2004) Article DOI: 10.1021/jm0498203 BindingDB Entry DOI: 10.7270/Q2HM57XC
					More data for this Ligand-Target Pair
Histamine H2 receptor (Homo sapiens (Human))	BDBM50156858 (3-{4-[6-fluoro-1-(2-methoxyethyl)-1H-indol-3-yl]pi...) Show SMILES COCCn1cc(C2CCN(Cc3cccc(c3)C(O)=O)CC2)c2ccc(F)cc12 Show InChI InChI=1S/C24H27FN2O3/c1-30-12-11-27-16-22(21-6-5-20(25)14-23(21)27)18-7-9-26(10-8-18)15-17-3-2-4-19(13-17)24(28)29/h2-6,13-14,16,18H,7-12,15H2,1H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Displacement of [3H]ketanserine from histamine H2 receptor in human cortex membranes				J Med Chem 47: 6326-37 (2004) Article DOI: 10.1021/jm0498203 BindingDB Entry DOI: 10.7270/Q2HM57XC
					More data for this Ligand-Target Pair