null

SMILES: OC(=O)c1ccccc1OCCN1CCC(CC1)c1cn(Cc2ccc(Cl)s2)c2ccccc12

InChI Key: InChIKey=VYHLLXUPTFDIMK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50156882   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50156882 (2-(2-(4-(1-((5-chlorothiophen-2-yl)methyl)-1H-indo...) Show SMILES OC(=O)c1ccccc1OCCN1CCC(CC1)c1cn(Cc2ccc(Cl)s2)c2ccccc12 Show InChI InChI=1S/C27H27ClN2O3S/c28-26-10-9-20(34-26)17-30-18-23(21-5-1-3-7-24(21)30)19-11-13-29(14-12-19)15-16-33-25-8-4-2-6-22(25)27(31)32/h1-10,18-19H,11-17H2,(H,31,32)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	295	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibitory concentration against histamine-H1 receptor				Bioorg Med Chem Lett 15: 1165-7 (2005) Article DOI: 10.1016/j.bmcl.2004.12.008 BindingDB Entry DOI: 10.7270/Q2HX1C5R
					More data for this Ligand-Target Pair
Histamine H2 receptor (Homo sapiens (Human))	BDBM50156882 (2-(2-(4-(1-((5-chlorothiophen-2-yl)methyl)-1H-indo...) Show SMILES OC(=O)c1ccccc1OCCN1CCC(CC1)c1cn(Cc2ccc(Cl)s2)c2ccccc12 Show InChI InChI=1S/C27H27ClN2O3S/c28-26-10-9-20(34-26)17-30-18-23(21-5-1-3-7-24(21)30)19-11-13-29(14-12-19)15-16-33-25-8-4-2-6-22(25)27(31)32/h1-10,18-19H,11-17H2,(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.86E+3	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Displacement of [3H]ketanserine from histamine H2 receptor in human cortex membranes				J Med Chem 47: 6326-37 (2004) Article DOI: 10.1021/jm0498203 BindingDB Entry DOI: 10.7270/Q2HM57XC
					More data for this Ligand-Target Pair
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50156882 (2-(2-(4-(1-((5-chlorothiophen-2-yl)methyl)-1H-indo...) Show SMILES OC(=O)c1ccccc1OCCN1CCC(CC1)c1cn(Cc2ccc(Cl)s2)c2ccccc12 Show InChI InChI=1S/C27H27ClN2O3S/c28-26-10-9-20(34-26)17-30-18-23(21-5-1-3-7-24(21)30)19-11-13-29(14-12-19)15-16-33-25-8-4-2-6-22(25)27(31)32/h1-10,18-19H,11-17H2,(H,31,32)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Displacement of [3H]mepyramine from histamine H1 receptor in guinea pig cerebellum membranes				J Med Chem 47: 6326-37 (2004) Article DOI: 10.1021/jm0498203 BindingDB Entry DOI: 10.7270/Q2HM57XC
					More data for this Ligand-Target Pair