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SMILES: CCOCCn1cc(C2CCN(CCOc3ccccc3C(O)=O)CC2)c2cccc(C)c12

InChI Key: InChIKey=WIQGPOWORKUTND-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50156888   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50156888 (2-(2-(4-(1-(2-ethoxyethyl)-7-methyl-1H-indol-3-yl)...) Show SMILES CCOCCn1cc(C2CCN(CCOc3ccccc3C(O)=O)CC2)c2cccc(C)c12 Show InChI InChI=1S/C27H34N2O4/c1-3-32-17-16-29-19-24(22-9-6-7-20(2)26(22)29)21-11-13-28(14-12-21)15-18-33-25-10-5-4-8-23(25)27(30)31/h4-10,19,21H,3,11-18H2,1-2H3,(H,30,31)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Displacement of [3H]mepyramine from histamine H1 receptor in guinea pig cerebellum membranes				J Med Chem 47: 6326-37 (2004) Article DOI: 10.1021/jm0498203 BindingDB Entry DOI: 10.7270/Q2HM57XC
					More data for this Ligand-Target Pair
Histamine H2 receptor (Homo sapiens (Human))	BDBM50156888 (2-(2-(4-(1-(2-ethoxyethyl)-7-methyl-1H-indol-3-yl)...) Show SMILES CCOCCn1cc(C2CCN(CCOc3ccccc3C(O)=O)CC2)c2cccc(C)c12 Show InChI InChI=1S/C27H34N2O4/c1-3-32-17-16-29-19-24(22-9-6-7-20(2)26(22)29)21-11-13-28(14-12-21)15-18-33-25-10-5-4-8-23(25)27(30)31/h4-10,19,21H,3,11-18H2,1-2H3,(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Displacement of [3H]ketanserine from histamine H2 receptor in human cortex membranes				J Med Chem 47: 6326-37 (2004) Article DOI: 10.1021/jm0498203 BindingDB Entry DOI: 10.7270/Q2HM57XC
					More data for this Ligand-Target Pair