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Enter Data

BDBM50157088 6-[2-(3-Isopropoxy-phenyl)-cyclopropyl]-naphthalene-2-carboxamidine::CHEMBL182309

SMILES: CC(C)Oc1cccc(c1)C1CC1c1ccc2cc(ccc2c1)C(N)=N

InChI Key: InChIKey=AIYYJNSOLWDMRN-UHFFFAOYSA-N

Data: 5 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50157088
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Trypsin (Sus scrofa)	BDBM50157088 (6-[2-(3-Isopropoxy-phenyl)-cyclopropyl]-naphthalen...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	141	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity value against trypsin				Bioorg Med Chem Lett 15: 93-8 (2004) Article DOI: 10.1016/j.bmcl.2004.10.026 BindingDB Entry DOI: 10.7270/Q2R210W5
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50157088 (6-[2-(3-Isopropoxy-phenyl)-cyclopropyl]-naphthalen...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	263	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity value against urokinase plasminogen activator				Bioorg Med Chem Lett 15: 93-8 (2004) Article DOI: 10.1016/j.bmcl.2004.10.026 BindingDB Entry DOI: 10.7270/Q2R210W5
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Kallikrein-1 (Homo sapiens (Human))	BDBM50157088 (6-[2-(3-Isopropoxy-phenyl)-cyclopropyl]-naphthalen...) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity value against kallikrein				Bioorg Med Chem Lett 15: 93-8 (2004) Article DOI: 10.1016/j.bmcl.2004.10.026 BindingDB Entry DOI: 10.7270/Q2R210W5
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50157088 (6-[2-(3-Isopropoxy-phenyl)-cyclopropyl]-naphthalen...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.45E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity value against plasmin				Bioorg Med Chem Lett 15: 93-8 (2004) Article DOI: 10.1016/j.bmcl.2004.10.026 BindingDB Entry DOI: 10.7270/Q2R210W5
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM50157088 (6-[2-(3-Isopropoxy-phenyl)-cyclopropyl]-naphthalen...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.19E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity value against Tissue plasminogen activator				Bioorg Med Chem Lett 15: 93-8 (2004) Article DOI: 10.1016/j.bmcl.2004.10.026 BindingDB Entry DOI: 10.7270/Q2R210W5
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair