BDBM50157103 6-[2-(1,2-Dimethyl-1,2,3,4-tetrahydro-isoquinolin-7-yl)-cyclopropyl]-naphthalene-2-carboxamidine::CHEMBL362671

SMILES: CC1N(C)CCc2ccc(cc12)C1CC1c1ccc2cc(ccc2c1)C(N)=N

InChI Key: InChIKey=BRZMIZNCFORRIR-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50157103   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50157103 (6-[2-(1,2-Dimethyl-1,2,3,4-tetrahydro-isoquinolin-...) Show SMILES CC1N(C)CCc2ccc(cc12)C1CC1c1ccc2cc(ccc2c1)C(N)=N Show InChI InChI=1S/C25H27N3/c1-15-22-13-20(6-3-16(22)9-10-28(15)2)24-14-23(24)19-7-4-18-12-21(25(26)27)8-5-17(18)11-19/h3-8,11-13,15,23-24H,9-10,14H2,1-2H3,(H3,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	293	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity value against urokinase plasminogen activator				Bioorg Med Chem Lett 15: 93-8 (2004) Article DOI: 10.1016/j.bmcl.2004.10.026 BindingDB Entry DOI: 10.7270/Q2R210W5
					More data for this Ligand-Target Pair