BDBM50157206 (1Z)-1-(3,4-dichlorophenyl)-2-phenoxyethan-1-one thiosemicarbazone::CHEMBL182790

SMILES: NC(=S)NN=C(COc1ccccc1)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=FIJYOQYJGIYCIK-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50157206   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Falcipain-2 (Plasmodium falciparum)	BDBM50157206 ((1Z)-1-(3,4-dichlorophenyl)-2-phenoxyethan-1-one t...) Show SMILES NC(=S)NN=C(COc1ccccc1)c1ccc(Cl)c(Cl)c1 |w:4.3| Show InChI InChI=1S/C15H13Cl2N3OS/c16-12-7-6-10(8-13(12)17)14(19-20-15(18)22)9-21-11-4-2-1-3-5-11/h1-8H,9H2,(H3,18,20,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	375	n/a	n/a	n/a	n/a	n/a	n/a
University of California-San Francisco Curated by ChEMBL					Assay Description Inhibitory concentration against falcipain-2 of Plasmodium falciparum W2				Bioorg Med Chem Lett 15: 121-3 (2004) Article DOI: 10.1016/j.bmcl.2004.10.023 BindingDB Entry DOI: 10.7270/Q2BV7G4K
					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM50157206 ((1Z)-1-(3,4-dichlorophenyl)-2-phenoxyethan-1-one t...) Show SMILES NC(=S)NN=C(COc1ccccc1)c1ccc(Cl)c(Cl)c1 |w:4.3| Show InChI InChI=1S/C15H13Cl2N3OS/c16-12-7-6-10(8-13(12)17)14(19-20-15(18)22)9-21-11-4-2-1-3-5-11/h1-8H,9H2,(H3,18,20,22)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
University of California-San Francisco Curated by ChEMBL					Assay Description Inhibitory concentration against cruzain of Trypanosoma cruzi				Bioorg Med Chem Lett 15: 121-3 (2004) Article DOI: 10.1016/j.bmcl.2004.10.023 BindingDB Entry DOI: 10.7270/Q2BV7G4K
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50157206 ((1Z)-1-(3,4-dichlorophenyl)-2-phenoxyethan-1-one t...) Show SMILES NC(=S)NN=C(COc1ccccc1)c1ccc(Cl)c(Cl)c1 |w:4.3| Show InChI InChI=1S/C15H13Cl2N3OS/c16-12-7-6-10(8-13(12)17)14(19-20-15(18)22)9-21-11-4-2-1-3-5-11/h1-8H,9H2,(H3,18,20,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
University of California-San Francisco Curated by ChEMBL					Assay Description Inhibitory concentration against rhodesain of Trypanosoma brucei rhodesience				Bioorg Med Chem Lett 15: 121-3 (2004) Article DOI: 10.1016/j.bmcl.2004.10.023 BindingDB Entry DOI: 10.7270/Q2BV7G4K
					More data for this Ligand-Target Pair