BDBM50157210 (E)-(3,4-dichlorophenyl)(2-phenylcyclopropyl)methanone thiosemicarbazone::CHEMBL183396

SMILES: NC(=S)NN=C(C1CC1c1ccccc1)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=DIOJIFYCWQBZFF-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50157210   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Falcipain-2 (Plasmodium falciparum)	BDBM50157210 ((E)-(3,4-dichlorophenyl)(2-phenylcyclopropyl)metha...) Show SMILES NC(=S)NN=C(C1CC1c1ccccc1)c1ccc(Cl)c(Cl)c1 |w:4.3| Show InChI InChI=1S/C17H15Cl2N3S/c18-14-7-6-11(8-15(14)19)16(21-22-17(20)23)13-9-12(13)10-4-2-1-3-5-10/h1-8,12-13H,9H2,(H3,20,22,23)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
University of California-San Francisco Curated by ChEMBL					Assay Description Inhibitory concentration against falcipain-2 of Plasmodium falciparum W2				Bioorg Med Chem Lett 15: 121-3 (2004) Article DOI: 10.1016/j.bmcl.2004.10.023 BindingDB Entry DOI: 10.7270/Q2BV7G4K
					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM50157210 ((E)-(3,4-dichlorophenyl)(2-phenylcyclopropyl)metha...) Show SMILES NC(=S)NN=C(C1CC1c1ccccc1)c1ccc(Cl)c(Cl)c1 |w:4.3| Show InChI InChI=1S/C17H15Cl2N3S/c18-14-7-6-11(8-15(14)19)16(21-22-17(20)23)13-9-12(13)10-4-2-1-3-5-10/h1-8,12-13H,9H2,(H3,20,22,23)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
University of California-San Francisco Curated by ChEMBL					Assay Description Inhibitory concentration against cruzain of Trypanosoma cruzi				Bioorg Med Chem Lett 15: 121-3 (2004) Article DOI: 10.1016/j.bmcl.2004.10.023 BindingDB Entry DOI: 10.7270/Q2BV7G4K
					More data for this Ligand-Target Pair
Rhodesain (Trypanosoma brucei rhodesiense)	BDBM50157210 ((E)-(3,4-dichlorophenyl)(2-phenylcyclopropyl)metha...) Show SMILES NC(=S)NN=C(C1CC1c1ccccc1)c1ccc(Cl)c(Cl)c1 |w:4.3| Show InChI InChI=1S/C17H15Cl2N3S/c18-14-7-6-11(8-15(14)19)16(21-22-17(20)23)13-9-12(13)10-4-2-1-3-5-10/h1-8,12-13H,9H2,(H3,20,22,23)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
University of California-San Francisco Curated by ChEMBL					Assay Description Inhibitory concentration against rhodesain of Trypanosoma brucei rhodesience				Bioorg Med Chem Lett 15: 121-3 (2004) Article DOI: 10.1016/j.bmcl.2004.10.023 BindingDB Entry DOI: 10.7270/Q2BV7G4K
					More data for this Ligand-Target Pair