BDBM50157430 CHEMBL3781271
SMILES: C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(Br)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCC[N+](C)(C)C)C(=O)N[C@@H](CO)C(N)=O
InChI Key: InChIKey=PBXKOVFJOWCAAC-JGLPLDBMSA-O
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Chromobox protein homolog 7 (Homo sapiens (Human)) | BDBM50157430 (CHEMBL3781271) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Victoria Curated by ChEMBL | Assay Description Binding affinity to N-terminal His6-tagged human CBX7 (8 to 62) expressed in Escherichia coli BL21 using FITC-peptide-3 as competitive binding probe ... | ACS Med Chem Lett 7: 139-44 (2016) BindingDB Entry DOI: 10.7270/Q2222WNZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chromobox protein homolog 8 (Homo sapiens (Human)) | BDBM50157430 (CHEMBL3781271) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Victoria Curated by ChEMBL | Assay Description Inhibition of CBX8 (unknown origin) assessed as inhibition of CBX4 disruption by competitive FP assay | Bioorg Med Chem 28: (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chromobox protein homolog 7 (Homo sapiens (Human)) | BDBM50157430 (CHEMBL3781271) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Victoria Curated by ChEMBL | Assay Description Inhibition of CBX7 (unknown origin) assessed as inhibition of CBX4 disruption by competitive FP assay | Bioorg Med Chem 28: (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chromobox protein homolog 6 (Homo sapiens (Human)) | BDBM50157430 (CHEMBL3781271) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Victoria Curated by ChEMBL | Assay Description Inhibition of CBX6 (unknown origin) assessed as inhibition of CBX4 disruption by competitive FP assay | Bioorg Med Chem 28: (2020) | |||||||||||
More data for this Ligand-Target Pair |