null

SMILES: Oc1ccc(-c2nn(CC=C)c3c(cccc23)C(F)(F)F)c(O)c1

InChI Key: InChIKey=ZDUDMCQPFKPISO-UHFFFAOYSA-N

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50157493   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Homo sapiens (Human))	BDBM50157493 (4-[1-allyl-7-(trifluoromethyl)-1H-indazol-3-yl]ben...) Show SMILES Oc1ccc(-c2nn(CC=C)c3c(cccc23)C(F)(F)F)c(O)c1 Show InChI InChI=1S/C17H13F3N2O2/c1-2-8-22-16-12(4-3-5-13(16)17(18,19)20)15(21-22)11-7-6-10(23)9-14(11)24/h2-7,9,23-24H,1,8H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]E2 from ERalpha ligand binding domain				J Med Chem 47: 6435-8 (2004) Article DOI: 10.1021/jm049194+ BindingDB Entry DOI: 10.7270/Q2639P7B
					More data for this Ligand-Target Pair				3D Structure (crystal)
Estrogen receptor beta (Homo sapiens (Human))	BDBM50157493 (4-[1-allyl-7-(trifluoromethyl)-1H-indazol-3-yl]ben...) Show SMILES Oc1ccc(-c2nn(CC=C)c3c(cccc23)C(F)(F)F)c(O)c1 Show InChI InChI=1S/C17H13F3N2O2/c1-2-8-22-16-12(4-3-5-13(16)17(18,19)20)15(21-22)11-7-6-10(23)9-14(11)24/h2-7,9,23-24H,1,8H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	106	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]E2 from ERbeta ligand binding domain				J Med Chem 47: 6435-8 (2004) Article DOI: 10.1021/jm049194+ BindingDB Entry DOI: 10.7270/Q2639P7B
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50157493 (4-[1-allyl-7-(trifluoromethyl)-1H-indazol-3-yl]ben...) Show SMILES Oc1ccc(-c2nn(CC=C)c3c(cccc23)C(F)(F)F)c(O)c1 Show InChI InChI=1S/C17H13F3N2O2/c1-2-8-22-16-12(4-3-5-13(16)17(18,19)20)15(21-22)11-7-6-10(23)9-14(11)24/h2-7,9,23-24H,1,8H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcription				J Med Chem 47: 6435-8 (2004) Article DOI: 10.1021/jm049194+ BindingDB Entry DOI: 10.7270/Q2639P7B
					More data for this Ligand-Target Pair				3D Structure (crystal)