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SMILES: Cc1cc(O)ccc1-c1nn(CC=C)c2c(cccc12)C(F)(F)F

InChI Key: InChIKey=SWJSHDFDYLZVEN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50157507   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Estrogen receptor


(Homo sapiens (Human))		BDBM50157507
PNG
(4-[1-allyl-7-(trifluoromethyl)-1H-indazol-3-yl]-3-...)
Show SMILES Cc1cc(O)ccc1-c1nn(CC=C)c2c(cccc12)C(F)(F)F
Show InChI InChI=1S/C18H15F3N2O/c1-3-9-23-17-14(5-4-6-15(17)18(19,20)21)16(22-23)13-8-7-12(24)10-11(13)2/h3-8,10,24H,1,9H2,2H3
PDB

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antibodypedia
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 59n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcription

J Med Chem 47: 6435-8 (2004)


Article DOI: 10.1021/jm049194+
BindingDB Entry DOI: 10.7270/Q2639P7B
More data for this
Ligand-Target Pair