BDBM50157633 CHEMBL3779949
SMILES: CC1CN(CCC2CCN(Cc3ccccc3)CC2)C(=O)N(C1)c1cccc(c1)C(N)=N
InChI Key: InChIKey=QGQKKJOSTCJRNL-UHFFFAOYSA-N
Data: 6 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Coagulation factor X (Homo sapiens (Human)) | BDBM50157633 (CHEMBL3779949) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Curated by ChEMBL | Assay Description Inhibition of human recombinant factor 10a using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis | ACS Med Chem Lett 7: 177-81 (2016) BindingDB Entry DOI: 10.7270/Q2Z60QZM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Matriptase (Homo sapiens (Human)) | BDBM50157633 (CHEMBL3779949) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 510 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Curated by ChEMBL | Assay Description Inhibition of human recombinant matripase catalytic domain using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis | ACS Med Chem Lett 7: 177-81 (2016) BindingDB Entry DOI: 10.7270/Q2Z60QZM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor activator (Homo sapiens (Human)) | BDBM50157633 (CHEMBL3779949) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Curated by ChEMBL | Assay Description Inhibition of human recombinant hepatocyte growth factor activator using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis | ACS Med Chem Lett 7: 177-81 (2016) BindingDB Entry DOI: 10.7270/Q2Z60QZM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepsin (Homo sapiens (Human)) | BDBM50157633 (CHEMBL3779949) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Curated by ChEMBL | Assay Description Inhibition of human recombinant hepsin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis | ACS Med Chem Lett 7: 177-81 (2016) BindingDB Entry DOI: 10.7270/Q2Z60QZM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin (Homo sapiens (Human)) | BDBM50157633 (CHEMBL3779949) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.77E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Curated by ChEMBL | Assay Description Inhibition of human recombinant trypsin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis | ACS Med Chem Lett 7: 177-81 (2016) BindingDB Entry DOI: 10.7270/Q2Z60QZM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50157633 (CHEMBL3779949) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Curated by ChEMBL | Assay Description Inhibition of human recombinant thrombin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis | ACS Med Chem Lett 7: 177-81 (2016) BindingDB Entry DOI: 10.7270/Q2Z60QZM | |||||||||||
More data for this Ligand-Target Pair |