BDBM50157736 3-((5-(2,3-dihydroxybenzylideneamino)naphthalen-1-ylimino)methyl)benzene-1,2-diol::CHEMBL222325
SMILES: Oc1cccc(\C=N\c2cccc3c(cccc23)\N=C/c2cccc(O)c2O)c1O
InChI Key: InChIKey=VWUYUSOZBGBSRJ-KGRJIBJCSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Falcipain-2 (Plasmodium falciparum) | BDBM50157736 (3-((5-(2,3-dihydroxybenzylideneamino)naphthalen-1-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Mississippi Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum recombinant falcipain-2 | J Med Chem 47: 6609-15 (2004) Article DOI: 10.1021/jm0493717 BindingDB Entry DOI: 10.7270/Q2GT5P0D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cysteine protease falcipain-3 (Plasmodium falciparum) | BDBM50157736 (3-((5-(2,3-dihydroxybenzylideneamino)naphthalen-1-...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Mississippi Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum recombinant falcipain-3 | J Med Chem 47: 6609-15 (2004) Article DOI: 10.1021/jm0493717 BindingDB Entry DOI: 10.7270/Q2GT5P0D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cysteine protease (Leishmania donovani) | BDBM50157736 (3-((5-(2,3-dihydroxybenzylideneamino)naphthalen-1-...) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.13E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Mississippi Curated by ChEMBL | Assay Description Inhibition of Leishmania donovani cysteine protease | J Med Chem 47: 6609-15 (2004) Article DOI: 10.1021/jm0493717 BindingDB Entry DOI: 10.7270/Q2GT5P0D | |||||||||||
More data for this Ligand-Target Pair |