BDBM50157748 1-(naphthalen-2-ylsulfonyl)-4-(propylsulfonyl)piperazine::CHEMBL224858
SMILES: CCCS(=O)(=O)N1CCN(CC1)S(=O)(=O)c1ccc2ccccc2c1
InChI Key: InChIKey=WUMXZKFGHMFXQP-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Falcipain-2 (Plasmodium falciparum) | BDBM50157748 (1-(naphthalen-2-ylsulfonyl)-4-(propylsulfonyl)pipe...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.24E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Mississippi Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum recombinant falcipain-2 | J Med Chem 47: 6609-15 (2004) Article DOI: 10.1021/jm0493717 BindingDB Entry DOI: 10.7270/Q2GT5P0D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cysteine protease falcipain-3 (Plasmodium falciparum) | BDBM50157748 (1-(naphthalen-2-ylsulfonyl)-4-(propylsulfonyl)pipe...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.96E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Mississippi Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum recombinant falcipain-3 | J Med Chem 47: 6609-15 (2004) Article DOI: 10.1021/jm0493717 BindingDB Entry DOI: 10.7270/Q2GT5P0D | |||||||||||
More data for this Ligand-Target Pair |