BDBM50157760 CHEMBL438659::N2',N6'-bis(2-hydroxybenzylidene)pyridine-2,6-dicarbohydrazide

SMILES: Oc1ccccc1C=NNC(=O)c1cccc(n1)C(=O)NN=Cc1ccccc1O

InChI Key: InChIKey=KEBDPIKQAMFVSI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50157760   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Falcipain-2 (Plasmodium falciparum)	BDBM50157760 (CHEMBL438659 | N2',N6'-bis(2-hydroxybenzylidene)py...) Show SMILES Oc1ccccc1C=NNC(=O)c1cccc(n1)C(=O)NN=Cc1ccccc1O |w:8.9,22.24| Show InChI InChI=1S/C21H17N5O4/c27-18-10-3-1-6-14(18)12-22-25-20(29)16-8-5-9-17(24-16)21(30)26-23-13-15-7-2-4-11-19(15)28/h1-13,27-28H,(H,25,29)(H,26,30)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum recombinant falcipain-2				J Med Chem 47: 6609-15 (2004) Article DOI: 10.1021/jm0493717 BindingDB Entry DOI: 10.7270/Q2GT5P0D
					More data for this Ligand-Target Pair
Cysteine protease falcipain-3 (Plasmodium falciparum)	BDBM50157760 (CHEMBL438659 | N2',N6'-bis(2-hydroxybenzylidene)py...) Show SMILES Oc1ccccc1C=NNC(=O)c1cccc(n1)C(=O)NN=Cc1ccccc1O |w:8.9,22.24| Show InChI InChI=1S/C21H17N5O4/c27-18-10-3-1-6-14(18)12-22-25-20(29)16-8-5-9-17(24-16)21(30)26-23-13-15-7-2-4-11-19(15)28/h1-13,27-28H,(H,25,29)(H,26,30)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum recombinant falcipain-3				J Med Chem 47: 6609-15 (2004) Article DOI: 10.1021/jm0493717 BindingDB Entry DOI: 10.7270/Q2GT5P0D
					More data for this Ligand-Target Pair