BDBM50157841 7-Biphenyl-4-yl-3-hydroxy-1H-furo[3,2-d]pyrimidine-2,4-dione::CHEMBL364591

SMILES: On1c(=O)[nH]c2c(coc2c1=O)-c1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=ULQLXBVELCEFAO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50157841   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Flap endonuclease 1 (Homo sapiens (Human))	BDBM50157841 (7-Biphenyl-4-yl-3-hydroxy-1H-furo[3,2-d]pyrimidine...) Show SMILES On1c(=O)[nH]c2c(coc2c1=O)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C18H12N2O4/c21-17-16-15(19-18(22)20(17)23)14(10-24-16)13-8-6-12(7-9-13)11-4-2-1-3-5-11/h1-10,23H,(H,19,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.0230	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against the Flap endonuclease-1				Bioorg Med Chem Lett 15: 277-81 (2004) Article DOI: 10.1016/j.bmcl.2004.10.086 BindingDB Entry DOI: 10.7270/Q2HD7V46
					More data for this Ligand-Target Pair
DNA excision repair protein ERCC-5 (Homo sapiens (Human))	BDBM50157841 (7-Biphenyl-4-yl-3-hydroxy-1H-furo[3,2-d]pyrimidine...) Show SMILES On1c(=O)[nH]c2c(coc2c1=O)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C18H12N2O4/c21-17-16-15(19-18(22)20(17)23)14(10-24-16)13-8-6-12(7-9-13)11-4-2-1-3-5-11/h1-10,23H,(H,19,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.136	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against the xeroderma pigmentosum G				Bioorg Med Chem Lett 15: 277-81 (2004) Article DOI: 10.1016/j.bmcl.2004.10.086 BindingDB Entry DOI: 10.7270/Q2HD7V46
					More data for this Ligand-Target Pair